Abstract: The Chinese path to modernization requires the modernization of knowledge production through the construction of a self-developed knowledge system in China. The cultural dependence of knowledge production and the strategic value of knowledge systems determine the foundational role of cultural subjectivity in the construction of China’s self-developed knowledge system. The theoretical innovation of the CPC embodies the nationality, integrality, standardization, and interactivity of China’s self-developed knowledge system, which correspondingly demands that cultural subjects possess consciousness, innovation, mission, and practicality. In the practice of theoretical innovation, the CPC has successfully constructed an organic system of cultural subjects. By combining rational awakening with emotional awakening, the CPC achieves motivation stimulation. By integrating process construction with outcome refinement, it enhances its capabilities; by combining the“two integrations”and“extensive dialogue”, it maintains the vitality of construction; and by balancing individual autonomy and overall leadership, it ensures effectiveness. Thus, the CPC can promote the effective realization of cultural subjectivity in the construction of China’s self-developed knowledge system.

Key words: China’s independent knowledge system, cultural subjectivity, two integrations”, theoretical innovation of the Communist Party of China, knowledge production