Abstract: Faced with the real environment of domestic and foreign economic risks superposition, it is of great significance to study how to promote the high-quality development of China's manufacturing industry through the improvement of the resilience of the manufacturing industry. From the perspective of industrial adaptive structure adjustment, this paper discusses the theoretical mechanism of the manufacturing spatial agglomeration affecting the manufacturing resilience, and it makes an empirical analysis by using the data of China's prefecture level cities from 2008 to 2017. The results show that manufacturing spatial agglomeration has significantly improved the manufacturing resilience of China. After changing the core variables, transforming the model estimation methods and eliminating the sample selective bias, the conclusion is still robust. The heterogeneity analysis shows that the manufacturing spatial agglomeration can significantly promote the resilience of the manufacturing industry in large-scale cities, but has no significant positive effect on the resilience of the manufacturing industry in small and medium-sized cities. Further research shows that the manufacturing spatial agglomeration can promote the resilience of China's manufacturing industry by stimulating the entrepreneur's innovation spirit and inhibiting the low-quality entrepreneurial behaviors. This indicates that a reasonable guide to the development of the manufacturing spatial agglomeration will help to enhance the ability of the manufacturing industry to resist internal and external economic risks.

Key words: spatial agglomeration, manufacturing resilience, adaptive structural adjustment, entrepreneurship